Junior and senior faculty interested in broadening their investigative
research in the area of Systems Biology are invited to apply for pilot grants
of up to $50,000 per year for two-year terms.
Doctoral scientists interested in fellowships to study the principles of
transcriptional regulatory networks are invited to apply.
See all Publications >
Mendelian Code for Complex Disease
GGSB MD-Ph.D. graduate student, David Blair, co- authored a study using over 100 million patient records to identify a nondegenerate code of deleterious variants in Mendelian loci that contributes to complex disease risk. The results were published in the September 26, 2013 issue of Cell.
National Centers for Systems biology program marks its 10th anniversary
The NIGMS National Centers for Systems Biology (NCSB) program enables cutting-edge systems biology research, training, education and outreach.To mark the program’s 10-year anniversary, NIGMS is hosting a special centers meeting (NIH, July 10-12th) that will highlight the program’s achievements.
CCSB welcomes the 2013 summer REU students
The 10-week Chicago Center for Systems Biology REU program kicked off this past Tuesday. Students will work in the labs of Kevin White, Michael Rust, Richard Carthew, Rick Morimoto and Ilya Ruvinsky, on projects ranging from circadian rhythms in cyanobacteria to Drosophila development.
An organismal stress-sensing surveillance system
Center Fellow Patricija van Oosten-Hawle, Rick Morimoto and colleagues find that protein-folding stress that occurs in one tissue impacts the proteostasis capacity of other tissues. Their work reveals the existence of a transcellular chaperone signaling response that integrates cell-specific and organismal responses to maintain organismal proteostasis in response to localized stress.
Center Investigator recognized for excellence in graduate teaching
The CCSB congratulates Ilya Ruvinsky, recipient of the University of Chicago’s 2013 Faculty Award for Excellence in Graduate Teaching and Mentoring.
Ilya discusses teaching experiences and approaches in an interview with Megan Doherty.
Translation and timekeeping
Center investigator Ravi Allada’s group finds that ATAXIN-2, an RNA-associated protein involved in neurodegenerative disease, is a translational activator of the rate-limiting clock component PERIOD. Their findings highlight the importance of mechanisms of translation regulation on the function of the circadian clock.
The paper by Lim and Allada was published in Science.