CCSB & STEM Education

Systems biology explains the origin and nature of properties and behaviors that emerge from interactions among networked parts. Successful investigations require the union of concepts, techniques, and tools from Science, Technology, Engineering, and Mathematics (STEM). Such a synthesis is possible because large amounts of experimental data inputted into mathematical models help make sense of complicated phenomena, such as embryonic pattern formation or kidney tumerogenesis.

Data sets may include:

• DNA and RNA sequences
• DNA replication assays
• gene expression measurements
• protein synthesis characteristics
• receptor binding profiles
• protein & chromatin modifications and structural dynamics
• molecular signaling interactions
• cell proliferation alterations
• and metabolite level changes.

Included in this mix are modulations in cellular and organismal traits that occur as a result of physiological change, disease initiation, biological growth, and molecular evolution.