Jobs

Recombineering Director

The Chicago Center for Systems Biology (CCSB) in the Institute for Genomics and Systems Biology (IGSB) at The University of Chicago, invites applications from outstanding Ph.D.-level scientists for the position of Director, Recombineering Core Facility. We seek an independent, creative scientist who can develop and implement advanced and novel DNA engineering technologies, protocols and methods for large-scale clone production in human cells and animals. Oversee project development through appropriate high throughput pipeline production of recombineering clones. Supervise the data management (input and analysis). Train laboratory personnel in the strategies for advanced DNA engineering methodologies, data management and analysis. Work with the Center’s Director and Research Director to assure that the core is running efficiently and to assure that lab personnel are appropriately trained in standard experimental techniques. The successful candidate will interface with the Center’s research investigators, conceptualize genomics projects, and oversee implementation by the scientific technical staff. Our exceptional collegiality and interdisciplinary collaborations make CCSB and IGSB an excellent environment for an innovative scientist who can benefit from and contribute to the rapid growth of Systems Biology at The University of Chicago.

The successful candidate will use her/his expertise, experience, and enthusiasm to guide the development of the CCSB recombineering core facility. This position will include a substantial budget, supervisory role over technical staff and the opportunity to collaborate with a team of experienced and innovative programmers, postdoctoral scholars, and graduate students.

The Chicago Center for Systems Biology is one of ten National Centers for Systems Biology funded by the National Institute of General Medical Sciences (NIGMS).

Minimum Qualifications

Master’s degree required; doctoral level degree in molecular cell biology and/or bio-engineering preferred; experience in advanced DNA engineering through homologous recombination and BAC transgenesiss in animal and human cells required; demonstrated excellence as evidenced by multiple high-profile journal publications preferred; excellent organizational and communications skills required; high level of motivation and ability to get along well with others required.

To Apply

Please send a cover letter detailing both your previous scientific work experience and your interest in this position, curriculum vitae, and contact information for three references to:

Aharon Solomon, Ph.D.
Research Director
Institute for Genomics & Systems Biology
The University of Chicago
428 CLSC
920 East 58th Street
Chicago, IL 60637
asolomon at uchicago.edu

Research Technologist

Perform duties as a Research Technologist in the Institute for Genomics & Systems Biology at the University of Chicago together with collaborators at other Chicago institutions. Join a team involved in target discovery and drug discovery in a genomics/high throughput biology laboratory. Use high throughput technology to perform drug discovery. Attend and participate in project meetings, summarize results of experiments performed and assist in interpreting the results of studies. Interact with students and other laboratory members and assist them with their work as directed by the PI. Essential Functions: 80% – Handling of human tissue samples and cell lines to perform high throughput screening. Use samples for a large variety of biochemical and molecular biology experiments. Use of samples for various high throughput experiments.

20% Provide logistical support for the smooth running of the lab (ordering, safety, organization). Maintain accurate written and electronic records of experiments performed. Perform general laboratory duties such as preparation of reagents. Provide daily maintenance of laboratory equipment and organization. Other Functions: The above statements are intended to describe the general nature and level of the work being performed by people assigned to this job. They are not an exhaustive list of all duties and responsibilities associated with it.

Minimum Qualifications

Bachelor's degree or higher in biology, chemistry, microbiology, biochemistry, or related field required; minimum one year of previous research experience preferred; experience with human tissue and cell culture preferred; experience in high throughput laboratory environment preferred; knowledge of automation/robotics preferred; knowledge of computers that includes Microsoft Excel and statistics preferred; excellent organizational skills and desire to maintain good relations with co-workers required. Mental Demands: Detailed work, problem solving, ability to work efficiently and to finish a work on time even in the face of unforeseen difficulties. Strong oral and written communications. Ability to multitask and to identify priorities. Physical Demands: Standing at lab bench for extended lengths of time, careful handling of microtiter plates and samples, extensive use of computer screens and fingering computer key boards, moderate lifting of laboratory equipment and supplies containers, exposure to hazardous chemicals, corrosive and toxic materials and biohazards associated with exposure to human and animal specimens.

To Apply

Please send a cover letter detailing both your previous scientific work experience and your interest in this position, curriculum vitae, and contact information for references to:

Ms. Liza Herendeen
The University of Chicago
900 E. 57th Street, KCBD 10100
Chicago, IL 60637
E-mail: igsb@bsd.uchicago.edu
Fax: 773-834-2877.